We’ve published a paper in Computational Statistics describing “A sparse hierarchical Bayesian model for detecting relevant antigenic sites in virus evolution”. This work, led by Vinny Davies and Dirk Husmeier (Glasgow Uni, school of Mathematics and Statistics), involved the development of a Bayesian model for identifying amino acid positions where substitutions are responsible for antigenic change. These substitutions enable viruses to escape existing immunity in the host population that arises following infection or vaccination.
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